The Protein Kinase TPL2 Is Essential for ERK1/ERK2 Activation and Cytokine Gene Expression in Airway Epithelial Cells Exposed to Pathogen-Associated Molecular Patterns (PAMPs)

The epithelium forms a physical barrier important to the detection of pathogens. P. aeruginosa infections are frequently encountered in Cystic Fibrosis lungs, lead to ERK1/ERK2 activation and contribute to tissue destruction. We report here that in bronchial airway epithelial cells (BEAS-2B), diffus...

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Detalles Bibliográficos
Autores principales: Martel, Guy, Bérubé, Julie, Rousseau, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602461/
https://www.ncbi.nlm.nih.gov/pubmed/23527104
http://dx.doi.org/10.1371/journal.pone.0059116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602461/
https://www.ncbi.nlm.nih.gov/pubmed/23527104
http://dx.doi.org/10.1371/journal.pone.0059116

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