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Identification of Small Molecule Activators of BMP Signaling
Bone Morphogenetic Proteins (BMPs) are morphogens that play a major role in regulating development and homeostasis. Although BMPs are used for the treatment of bone and kidney disorders, their clinical use is limited due to the supra-physiological doses required for therapeutic efficacy causing seve...
Autores principales: | Vrijens, Karen, Lin, Wenwei, Cui, Jimmy, Farmer, Dana, Low, Jonathan, Pronier, Elodie, Zeng, Fu-Yue, Shelat, Anang A., Guy, Kiplin, Taylor, Michael R., Chen, Taosheng, Roussel, Martine F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602516/ https://www.ncbi.nlm.nih.gov/pubmed/23527084 http://dx.doi.org/10.1371/journal.pone.0059045 |
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