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Safety and Immunogenicity of Heterologous Prime-Boost Immunisation with Plasmodium falciparum Malaria Candidate Vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in Healthy Gambian and Kenyan Adults

BACKGROUND: Heterologous prime boost immunization with chimpanzee adenovirus 63 (ChAd63) and Modified vaccinia Virus Ankara (MVA) vectored vaccines is a strategy recently shown to be capable of inducing strong cell mediated responses against several antigens from the malaria parasite. ChAd63-MVA exp...

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Detalles Bibliográficos
Autores principales: Ogwang, Caroline, Afolabi, Muhammed, Kimani, Domtila, Jagne, Ya Jankey, Sheehy, Susanne H., Bliss, Carly M., Duncan, Christopher J. A., Collins, Katharine A., Garcia Knight, Miguel A., Kimani, Eva, Anagnostou, Nicholas A., Berrie, Eleanor, Moyle, Sarah, Gilbert, Sarah C., Spencer, Alexandra J., Soipei, Peninah, Mueller, Jenny, Okebe, Joseph, Colloca, Stefano, Cortese, Riccardo, Viebig, Nicola K., Roberts, Rachel, Gantlett, Katherine, Lawrie, Alison M., Nicosia, Alfredo, Imoukhuede, Egeruan B., Bejon, Philip, Urban, Britta C., Flanagan, Katie L., Ewer, Katie J., Chilengi, Roma, Hill, Adrian V. S., Bojang, Kalifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602521/
https://www.ncbi.nlm.nih.gov/pubmed/23526949
http://dx.doi.org/10.1371/journal.pone.0057726