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Alterations in Prefrontal-Limbic Functional Activation and Connectivity in Chronic Stress-Induced Visceral Hyperalgesia
Repeated water avoidance stress (WAS) induces sustained visceral hyperalgesia (VH) in rats measured as enhanced visceromotor response to colorectal distension (CRD). This model incorporates two characteristic features of human irritable bowel syndrome (IBS), VH and a prominent role of stress in the...
Autores principales: | Wang, Zhuo, Ocampo, Marco A., Pang, Raina D., Bota, Mihail, Bradesi, Sylvie, Mayer, Emeran A., Holschneider, Daniel P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602545/ https://www.ncbi.nlm.nih.gov/pubmed/23527114 http://dx.doi.org/10.1371/journal.pone.0059138 |
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