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Effects of Lithium and Valproic Acid on Gene Expression and Phenotypic Markers in an NT2 Neurosphere Model of Neural Development

Mood stabilising drugs such as lithium (LiCl) and valproic acid (VPA) are the first line agents for treating conditions such as Bipolar disorder and Epilepsy. However, these drugs have potential developmental effects that are not fully understood. This study explores the use of a simple human neuros...

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Detalles Bibliográficos
Autores principales: Hill, Eric J., Nagel, David A., O’Neil, John D., Torr, Elizabeth, Woehrling, Elizabeth K., Devitt, Andrew, Coleman, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602582/
https://www.ncbi.nlm.nih.gov/pubmed/23527032
http://dx.doi.org/10.1371/journal.pone.0058822