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Effects of Lithium and Valproic Acid on Gene Expression and Phenotypic Markers in an NT2 Neurosphere Model of Neural Development
Mood stabilising drugs such as lithium (LiCl) and valproic acid (VPA) are the first line agents for treating conditions such as Bipolar disorder and Epilepsy. However, these drugs have potential developmental effects that are not fully understood. This study explores the use of a simple human neuros...
Autores principales: | Hill, Eric J., Nagel, David A., O’Neil, John D., Torr, Elizabeth, Woehrling, Elizabeth K., Devitt, Andrew, Coleman, Michael D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602582/ https://www.ncbi.nlm.nih.gov/pubmed/23527032 http://dx.doi.org/10.1371/journal.pone.0058822 |
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