Structural Model for the Interaction of a Designed Ankyrin Repeat Protein with the Human Epidermal Growth Factor Receptor 2

Designed Ankyrin Repeat Proteins are a class of novel binding proteins that can be selected and evolved to bind to targets with high affinity and specificity. We are interested in the DARPin H10-2-G3, which has been evolved to bind with very high affinity to the human epidermal growth factor recepto...

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Detalles Bibliográficos
Autores principales: Epa, V. Chandana, Dolezal, Olan, Doughty, Larissa, Xiao, Xiaowen, Jost, Christian, Plückthun, Andreas, Adams, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602593/
https://www.ncbi.nlm.nih.gov/pubmed/23527120
http://dx.doi.org/10.1371/journal.pone.0059163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602593/
https://www.ncbi.nlm.nih.gov/pubmed/23527120
http://dx.doi.org/10.1371/journal.pone.0059163

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