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Structural Model for the Interaction of a Designed Ankyrin Repeat Protein with the Human Epidermal Growth Factor Receptor 2
Designed Ankyrin Repeat Proteins are a class of novel binding proteins that can be selected and evolved to bind to targets with high affinity and specificity. We are interested in the DARPin H10-2-G3, which has been evolved to bind with very high affinity to the human epidermal growth factor recepto...
Autores principales: | Epa, V. Chandana, Dolezal, Olan, Doughty, Larissa, Xiao, Xiaowen, Jost, Christian, Plückthun, Andreas, Adams, Timothy E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602593/ https://www.ncbi.nlm.nih.gov/pubmed/23527120 http://dx.doi.org/10.1371/journal.pone.0059163 |
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