Ghrelin and the central regulation of feeding and energy balance

Ghrelin was discovered in 1999 as growth hormone secretagouge released from the gut. Soon after it was recognized that ghrelin is a fundamental driver of appetite in rodents and humans and that its mode of action requires alteration of hypothalamic circuit function. Here we review aspects of ghrelin...

Descripción completa

Detalles Bibliográficos
Autores principales: Abizaid, Alfonso, Horvath, Tamas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602992/
https://www.ncbi.nlm.nih.gov/pubmed/23565498
http://dx.doi.org/10.4103/2230-8210.105580
_version_ 1782263610384318464
author Abizaid, Alfonso
Horvath, Tamas L.
author_facet Abizaid, Alfonso
Horvath, Tamas L.
author_sort Abizaid, Alfonso
collection PubMed
description Ghrelin was discovered in 1999 as growth hormone secretagouge released from the gut. Soon after it was recognized that ghrelin is a fundamental driver of appetite in rodents and humans and that its mode of action requires alteration of hypothalamic circuit function. Here we review aspects of ghrelin's action that revolve around the central nervous system with the goal to highlight these pathways in integrative physiology of metabolism regulation including ghrelin's cross-talk with the action of the adipose hormone, leptin.
format Online
Article
Text
id pubmed-3602992
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-36029922013-04-05 Ghrelin and the central regulation of feeding and energy balance Abizaid, Alfonso Horvath, Tamas L. Indian J Endocrinol Metab Review Article Ghrelin was discovered in 1999 as growth hormone secretagouge released from the gut. Soon after it was recognized that ghrelin is a fundamental driver of appetite in rodents and humans and that its mode of action requires alteration of hypothalamic circuit function. Here we review aspects of ghrelin's action that revolve around the central nervous system with the goal to highlight these pathways in integrative physiology of metabolism regulation including ghrelin's cross-talk with the action of the adipose hormone, leptin. Medknow Publications & Media Pvt Ltd 2012-12 /pmc/articles/PMC3602992/ /pubmed/23565498 http://dx.doi.org/10.4103/2230-8210.105580 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Abizaid, Alfonso
Horvath, Tamas L.
Ghrelin and the central regulation of feeding and energy balance
title Ghrelin and the central regulation of feeding and energy balance
title_full Ghrelin and the central regulation of feeding and energy balance
title_fullStr Ghrelin and the central regulation of feeding and energy balance
title_full_unstemmed Ghrelin and the central regulation of feeding and energy balance
title_short Ghrelin and the central regulation of feeding and energy balance
title_sort ghrelin and the central regulation of feeding and energy balance
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602992/
https://www.ncbi.nlm.nih.gov/pubmed/23565498
http://dx.doi.org/10.4103/2230-8210.105580
work_keys_str_mv AT abizaidalfonso ghrelinandthecentralregulationoffeedingandenergybalance
AT horvathtamasl ghrelinandthecentralregulationoffeedingandenergybalance

Ejemplares similares