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Dipeptidyl Peptidase‐4 Inhibitors Attenuate Endothelial Function as Evaluated by Flow‐Mediated Vasodilatation in Type 2 Diabetic Patients

BACKGROUND: Endothelial dysfunction is an independent predictor for cardiovascular events in patients with type 2 diabetes (T2DM). Glucagon like peptide‐1 (GLP‐1) reportedly exerts vasodilatory actions, and inhibitors of dipeptidyl peptidase‐4 (DPP‐4), an enzyme‐degrading GLP‐1, are widely used to t...

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Detalles Bibliográficos
Autores principales: Ayaori, Makoto, Iwakami, Naotsugu, Uto‐Kondo, Harumi, Sato, Hiroki, Sasaki, Makoto, Komatsu, Tomohiro, Iizuka, Maki, Takiguchi, Shunichi, Yakushiji, Emi, Nakaya, Kazuhiro, Yogo, Makiko, Ogura, Masatsune, Takase, Bonpei, Murakami, Takehiko, Ikewaki, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603233/
https://www.ncbi.nlm.nih.gov/pubmed/23525426
http://dx.doi.org/10.1161/JAHA.112.003277