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Heart‐Specific Overexpression of Choline Acetyltransferase Gene Protects Murine Heart Against Ischemia Through Hypoxia‐Inducible Factor‐1α–Related Defense Mechanisms

BACKGROUND: Murine and human ventricular cardiomyocytes rich in acetylcholine (Ach) receptors are poorly innervated by the vagus, compared with whole ventricular innervation by the adrenergic nerve. However, vagal nerve stimulation produces a favorable outcome even in the murine heart, despite relat...

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Detalles Bibliográficos
Autores principales:	Kakinuma, Yoshihiko, Tsuda, Masayuki, Okazaki, Kayo, Akiyama, Tsuyoshi, Arikawa, Mikihiko, Noguchi, Tatsuya, Sato, Takayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603257/ https://www.ncbi.nlm.nih.gov/pubmed/23525439 http://dx.doi.org/10.1161/JAHA.112.004887

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