Dual Phases of Respiration Chain Defect-Augmented mROS-Mediated mCa(2+) Stress during Oxidative Insult in Normal and ρ (0) RBA1 Astrocytes

Mitochondrial respiratory chain (RC) deficits, resulting in augmented mitochondrial ROS (mROS) generation, underlie pathogenesis of astrocytes. However, mtDNA-depleted cells (ρ (0)) lacking RC have been reported to be either sensitive or resistant to apoptosis. In this study, we sought to determine...

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Detalles Bibliográficos
Autores principales: Peng, Tsung-I, Lin, Muh-Shi, Jou, Mei-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603293/
https://www.ncbi.nlm.nih.gov/pubmed/23533684
http://dx.doi.org/10.1155/2013/159567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603293/
https://www.ncbi.nlm.nih.gov/pubmed/23533684
http://dx.doi.org/10.1155/2013/159567

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