Linezolid Is Associated with Serotonin Syndrome in a Patient Receiving Amitriptyline, and Fentanyl: A Case Report and Review of the Literature

We report a unique case of an adverse interaction between the oxazolidinone antibiotic linezolid, the tricyclic antidepressant amitriptyline and the opioid analgesic fentanyl in a 68-year-old woman with advanced ischemic peripheral arterial disease and sepsis, under empirical antibiotic treatment. W...

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Detalles Bibliográficos
Autores principales: Samartzis, Lampros, Savvari, Paraskevi, Kontogiannis, Sofoklis, Dimopoulos, Stavros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603624/
https://www.ncbi.nlm.nih.gov/pubmed/23533900
http://dx.doi.org/10.1155/2013/617251
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author Samartzis, Lampros
Savvari, Paraskevi
Kontogiannis, Sofoklis
Dimopoulos, Stavros
author_facet Samartzis, Lampros
Savvari, Paraskevi
Kontogiannis, Sofoklis
Dimopoulos, Stavros
author_sort Samartzis, Lampros
collection PubMed
description We report a unique case of an adverse interaction between the oxazolidinone antibiotic linezolid, the tricyclic antidepressant amitriptyline and the opioid analgesic fentanyl in a 68-year-old woman with advanced ischemic peripheral arterial disease and sepsis, under empirical antibiotic treatment. We also summarize the current relevant literature as identified via PubMed, EMBASE, and PsycINFO as well as reference sections of selected articles.
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spelling pubmed-36036242013-03-26 Linezolid Is Associated with Serotonin Syndrome in a Patient Receiving Amitriptyline, and Fentanyl: A Case Report and Review of the Literature Samartzis, Lampros Savvari, Paraskevi Kontogiannis, Sofoklis Dimopoulos, Stavros Case Rep Psychiatry Case Report We report a unique case of an adverse interaction between the oxazolidinone antibiotic linezolid, the tricyclic antidepressant amitriptyline and the opioid analgesic fentanyl in a 68-year-old woman with advanced ischemic peripheral arterial disease and sepsis, under empirical antibiotic treatment. We also summarize the current relevant literature as identified via PubMed, EMBASE, and PsycINFO as well as reference sections of selected articles. Hindawi Publishing Corporation 2013 2013-03-04 /pmc/articles/PMC3603624/ /pubmed/23533900 http://dx.doi.org/10.1155/2013/617251 Text en Copyright © 2013 Lampros Samartzis et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Samartzis, Lampros
Savvari, Paraskevi
Kontogiannis, Sofoklis
Dimopoulos, Stavros
Linezolid Is Associated with Serotonin Syndrome in a Patient Receiving Amitriptyline, and Fentanyl: A Case Report and Review of the Literature
title Linezolid Is Associated with Serotonin Syndrome in a Patient Receiving Amitriptyline, and Fentanyl: A Case Report and Review of the Literature
title_full Linezolid Is Associated with Serotonin Syndrome in a Patient Receiving Amitriptyline, and Fentanyl: A Case Report and Review of the Literature
title_fullStr Linezolid Is Associated with Serotonin Syndrome in a Patient Receiving Amitriptyline, and Fentanyl: A Case Report and Review of the Literature
title_full_unstemmed Linezolid Is Associated with Serotonin Syndrome in a Patient Receiving Amitriptyline, and Fentanyl: A Case Report and Review of the Literature
title_short Linezolid Is Associated with Serotonin Syndrome in a Patient Receiving Amitriptyline, and Fentanyl: A Case Report and Review of the Literature
title_sort linezolid is associated with serotonin syndrome in a patient receiving amitriptyline, and fentanyl: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603624/
https://www.ncbi.nlm.nih.gov/pubmed/23533900
http://dx.doi.org/10.1155/2013/617251
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AT kontogiannissofoklis linezolidisassociatedwithserotoninsyndromeinapatientreceivingamitriptylineandfentanylacasereportandreviewoftheliterature
AT dimopoulosstavros linezolidisassociatedwithserotoninsyndromeinapatientreceivingamitriptylineandfentanylacasereportandreviewoftheliterature

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