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DNA Damage Sensor γ-H2AX Is Increased in Preneoplastic Lesions of Hepatocellular Carcinoma

Background. Phosphorylated histone H2AX (γ-H2AX) is a potential regulator of DNA repair and is a useful tool for detecting DNA damage. To evaluate the clinical usefulness of γ-H2AX in hepatocellular carcinoma (HCC), we measured the level of γ-H2AX in HCC, dysplastic nodule, and nontumorous liver dis...

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Detalles Bibliográficos
Autores principales:	Matsuda, Yasunobu, Wakai, Toshifumi, Kubota, Masayuki, Osawa, Mami, Takamura, Masaaki, Yamagiwa, Satoshi, Aoyagi, Yutaka, Sanpei, Ayumi, Fujimaki, Shun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603670/ https://www.ncbi.nlm.nih.gov/pubmed/23533353 http://dx.doi.org/10.1155/2013/597095

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