Conditional Genetic Elimination of Hepatocyte Growth Factor in Mice Compromises Liver Regeneration after Partial Hepatectomy

Hepatocyte growth factor (HGF) has been shown to be indispensable for liver regeneration because it serves as a main mitogenic stimulus driving hepatocytes toward proliferation. We hypothesized that ablating HGF in adult mice would have a negative effect on the ability of hepatocytes to regenerate....

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Detalles Bibliográficos
Autores principales: Nejak-Bowen, Kari, Orr, Anne, Bowen, William C., Michalopoulos, George K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603894/
https://www.ncbi.nlm.nih.gov/pubmed/23527275
http://dx.doi.org/10.1371/journal.pone.0059836

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