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Transporting Antitumor Drug Tamoxifen and Its Metabolites, 4-Hydroxytamoxifen and Endoxifen by Chitosan Nanoparticles

Synthetic and natural polymers are often used as drug delivery systems in vitro and in vivo. Biodegradable chitosan of different sizes were used to encapsulate antitumor drug tamoxifen (Tam) and its metabolites 4-hydroxytamoxifen (4-Hydroxytam) and endoxifen (Endox). The interactions of tamoxifen an...

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Detalles Bibliográficos
Autores principales:	Agudelo, Daniel, Sanyakamdhorn, Sriwanna, Nafisi, Shoherh, Tajmir-Riahi, Heidar-Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603901/ https://www.ncbi.nlm.nih.gov/pubmed/23527310 http://dx.doi.org/10.1371/journal.pone.0060250

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