Activating Somatic FGFR2 Mutations in Breast Cancer

It is known that FGFR2 gene variations confer a risk for breast cancer. FGFR2 and FGF10, the main ligand of FGFR2, are both overexpressed in 5–10% of breast tumors. In our study, we sequenced the most important coding regions of FGFR2 in somatic tumor tissue of 140 sporadic breast cancer patients an...

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Detalles Bibliográficos
Autores principales: Reintjes, Nadine, Li, Yun, Becker, Alexandra, Rohmann, Edyta, Schmutzler, Rita, Wollnik, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603931/
https://www.ncbi.nlm.nih.gov/pubmed/23527311
http://dx.doi.org/10.1371/journal.pone.0060264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603931/
https://www.ncbi.nlm.nih.gov/pubmed/23527311
http://dx.doi.org/10.1371/journal.pone.0060264

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