Toll-Like Receptor 7 Agonists: Chemical Feature Based Pharmacophore Identification and Molecular Docking Studies

Chemical feature based pharmacophore models were generated for Toll-like receptors 7 (TLR7) agonists using HypoGen algorithm, which is implemented in the Discovery Studio software. Several methods tools used in validation of pharmacophore model were presented. The first hypothesis Hypo1 was consider...

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Detalles Bibliográficos
Autores principales: Yu, Hui, Jin, Hongwei, Sun, Lidan, Zhang, Liangren, Sun, Gang, Wang, Zhanli, Yu, Yongchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603940/
https://www.ncbi.nlm.nih.gov/pubmed/23526932
http://dx.doi.org/10.1371/journal.pone.0056514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603940/
https://www.ncbi.nlm.nih.gov/pubmed/23526932
http://dx.doi.org/10.1371/journal.pone.0056514

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