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Properties and Molecular Determinants of the Natural Flavone Acacetin for Blocking hKv4.3 Channels

The natural flavone acacetin has been demonstrated to inhibit transient outward potassium current (I(to)) in human atrial myocytes. However, the molecular determinants of acacetin for blocking I(to) are unknown. The present study was designed to investigate the properties and molecular determinants...

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Detalles Bibliográficos
Autores principales: Wu, Hui-Jun, Sun, Hai-Ying, Wu, Wei, Zhang, Yan-Hui, Qin, Guo-Wei, Li, Gui-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603988/
https://www.ncbi.nlm.nih.gov/pubmed/23526953
http://dx.doi.org/10.1371/journal.pone.0057864