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Properties and Molecular Determinants of the Natural Flavone Acacetin for Blocking hKv4.3 Channels
The natural flavone acacetin has been demonstrated to inhibit transient outward potassium current (I(to)) in human atrial myocytes. However, the molecular determinants of acacetin for blocking I(to) are unknown. The present study was designed to investigate the properties and molecular determinants...
Autores principales: | Wu, Hui-Jun, Sun, Hai-Ying, Wu, Wei, Zhang, Yan-Hui, Qin, Guo-Wei, Li, Gui-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603988/ https://www.ncbi.nlm.nih.gov/pubmed/23526953 http://dx.doi.org/10.1371/journal.pone.0057864 |
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