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Comparative Studies of Copy Number Variation Detection Methods for Next-Generation Sequencing Technologies

Copy number variation (CNV) has played an important role in studies of susceptibility or resistance to complex diseases. Traditional methods such as fluorescence in situ hybridization (FISH) and array comparative genomic hybridization (aCGH) suffer from low resolution of genomic regions. Following t...

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Detalles Bibliográficos
Autores principales: Duan, Junbo, Zhang, Ji-Gang, Deng, Hong-Wen, Wang, Yu-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604020/
https://www.ncbi.nlm.nih.gov/pubmed/23527109
http://dx.doi.org/10.1371/journal.pone.0059128