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A 3-dimensional human embryonic stem cell (hESC)-derived model to detect developmental neurotoxicity of nanoparticles

Nanoparticles (NPs) have been shown to accumulate in organs, cross the blood–brain barrier and placenta, and have the potential to elicit developmental neurotoxicity (DNT). Here, we developed a human embryonic stem cell (hESC)-derived 3-dimensional (3-D) in vitro model that allows for testing of pot...

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Detalles Bibliográficos
Autores principales:	Hoelting, Lisa, Scheinhardt, Benjamin, Bondarenko, Olesja, Schildknecht, Stefan, Kapitza, Marion, Tanavde, Vivek, Tan, Betty, Lee, Qian Yi, Mecking, Stefan, Leist, Marcel, Kadereit, Suzanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2012
Materias:	In Vitro Systems
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604581/ https://www.ncbi.nlm.nih.gov/pubmed/23203475 http://dx.doi.org/10.1007/s00204-012-0984-2

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