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GFAP expression as an indicator of disease severity in mouse models of Alexander disease

AxD (Alexander disease) is a rare disorder caused by heterozygous mutations in GFAP (glial fibrillary acidic protein) resulting in accumulation of the GFAP protein and elevation of Gfap mRNA. To test whether GFAP itself can serve as a biomarker of disease status or progression, we investigated two i...

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Detalles Bibliográficos
Autores principales:	Jany, Paige L., Hagemann, Tracy L., Messing, Albee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Neurochemistry 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604736/ https://www.ncbi.nlm.nih.gov/pubmed/23432455 http://dx.doi.org/10.1042/AN20130003

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