Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans

Chronic exposure to high concentrations of hexavalent chromium (Cr(VI)) in drinking water causes intestinal adenomas and carcinomas in mice, but not in rats. Cr(VI) causes damage to intestinal villi and crypt hyperplasia in mice after only one week of exposure. After two years of exposure, intestina...

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Detalles Bibliográficos
Autores principales: Thompson, Chad M., Proctor, Deborah M., Suh, Mina, Haws, Laurie C., Kirman, Christopher R., Harris, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare USA, Inc. 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604738/
https://www.ncbi.nlm.nih.gov/pubmed/23445218
http://dx.doi.org/10.3109/10408444.2013.768596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604738/
https://www.ncbi.nlm.nih.gov/pubmed/23445218
http://dx.doi.org/10.3109/10408444.2013.768596

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