Cargando…

Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans

Chronic exposure to high concentrations of hexavalent chromium (Cr(VI)) in drinking water causes intestinal adenomas and carcinomas in mice, but not in rats. Cr(VI) causes damage to intestinal villi and crypt hyperplasia in mice after only one week of exposure. After two years of exposure, intestina...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thompson, Chad M., Proctor, Deborah M., Suh, Mina, Haws, Laurie C., Kirman, Christopher R., Harris, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Informa Healthcare USA, Inc. 2013
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604738/ https://www.ncbi.nlm.nih.gov/pubmed/23445218 http://dx.doi.org/10.3109/10408444.2013.768596

Ejemplares similares

A chronic oral reference dose for hexavalent chromium-induced intestinal cancer†
por: Thompson, Chad M, et al.
Publicado: (2014)

Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin‐of‐exposure values for hexavalent chromium
por: Thompson, Chad M., et al.
Publicado: (2017)

Comparison of Toxicity and Recovery in the Duodenum of B6C3F1 Mice Following Treatment with Intestinal Carcinogens Captan, Folpet, and Hexavalent Chromium
por: Thompson, Chad M., et al.
Publicado: (2017)

Application of the U.S. EPA Mode of Action Framework for Purposes of Guiding Future Research: A Case Study Involving the Oral Carcinogenicity of Hexavalent Chromium
por: Thompson, Chad M., et al.
Publicado: (2011)

Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of Action
por: Thompson, Chad M., et al.
Publicado: (2012)

Investigation of the Mode of Action Underlying the Tumorigenic Response Induced in B6C3F1 Mice Exposed Orally to Hexavalent Chromium
por: Thompson, Chad M., et al.
Publicado: (2011)

Assessment of Mechanistic Data for Hexavalent Chromium-Induced Rodent Intestinal Cancer Using the Key Characteristics of Carcinogens
por: Chappell, Grace A, et al.
Publicado: (2021)

Synchrotron-Based Imaging of Chromium and γ-H2AX Immunostaining in the Duodenum Following Repeated Exposure to Cr(VI) in Drinking Water
por: Thompson, Chad M., et al.
Publicado: (2015)

Crypt and Villus Transcriptomic Responses in Mouse Small Intestine Following Oral Exposure to Hexavalent Chromium
por: Chappell, Grace A, et al.
Publicado: (2021)

Genotoxicity of Tri- and Hexavalent Chromium Compounds In Vivo and Their Modes of Action on DNA Damage In Vitro
por: Fang, Zhijia, et al.
Publicado: (2014)

Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers
por: Proctor, Deborah M, et al.
Publicado: (2016)

Hexavalent chromium (Contaminants)
Publicado: (2019)

Assessment of the mode of action underlying development of liver lesions in mice following oral exposure to HFPO-DA and relevance to humans
por: Heintz, Melissa M, et al.
Publicado: (2023)

Letter to the Editor Regarding Banu et al. (2018). Chromium Accumulation on Human Placental Oxidative Stress and Apoptosis
por: Thompson, Chad M, et al.
Publicado: (2018)

Exposure to Environmentally Relevant Concentrations of Polystyrene Microplastics Increases Hexavalent Chromium Toxicity in Aquatic Animals
por: Kim, Jaehee, et al.
Publicado: (2022)

Biosorption of hexavalent chromium by Pleurotus ostreatus
por: da Rocha Ferreira, Glalber Luiz, et al.
Publicado: (2019)

Bioremediation of Hexavalent Chromium by Chromium Resistant Bacteria Reduces Phytotoxicity
por: Hossan, Shanewaz, et al.
Publicado: (2020)

The link between deacetylation and hepatotoxicity induced by exposure to hexavalent chromium
por: Yang, Qingyue, et al.
Publicado: (2021)

High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure
por: Rager, Julia E., et al.
Publicado: (2017)

Phytofabrication of Iron Nanoparticles for Hexavalent Chromium Remediation
por: Truskewycz, Adam, et al.
Publicado: (2018)

Adverse hematological effects of hexavalent chromium: an overview
por: Ray, Rina Rani
Publicado: (2016)

Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment
por: Thompson, Chad M., et al.
Publicado: (2016)

Absence of hexavalent chromium in marine carbonates: implications for chromium isotopes as paleoenvironment proxy
por: Fang, Ziyao, et al.
Publicado: (2020)

Assessment of Cr(VI)-Induced Cytotoxicity and Genotoxicity Using High Content Analysis
por: Thompson, Chad M., et al.
Publicado: (2012)

Reflections on hexavalent chromium: health hazards of an industrial heavyweight.
por: Pellerin, C, et al.
Publicado: (2000)

Shiny Science: A New Substitute for Hexavalent Chromium
por: Frazer, Lance
Publicado: (2006)

Inorganic nanoparticles for reduction of hexavalent chromium: Physicochemical aspects
por: Farooqi, Zahoor H., et al.
Publicado: (2021)

The Potential Contribution of Hexavalent Chromium to the Carcinogenicity of Chrysotile Asbestos
por: Walter, Martin, et al.
Publicado: (2022)

Chronic occupational exposure to hexavalent chromium causes DNA damage in electroplating workers
por: Zhang, Xu-Hui, et al.
Publicado: (2011)

Cytotoxic Effects of Hexavalent and Trivalent Chromium on Mammalian Cells In Vitro
por: Levis, A. G., et al.
Publicado: (1978)

Genetic Predisposition for Dermal Problems in Hexavalent Chromium Exposed Population
por: Sharma, Priti, et al.
Publicado: (2012)

Biosorption of Hexavalent Chromium from Aqueous Medium with Opuntia Biomass
por: Fernández-López, José A., et al.
Publicado: (2014)

Fluorescence-tunable copper nanoclusters and their application in hexavalent chromium sensing
por: Lin, Yu-Syuan, et al.
Publicado: (2019)

Immobilization of Hexavalent Chromium Using Self-Compacting Soil Technology
por: Rudzionis, Zymantas, et al.
Publicado: (2022)

Modeling of Hexavalent Chromium Removal with Hydrophobically Modified Cellulose Nanofibers
por: Ojembarrena, Francisco de Borja, et al.
Publicado: (2022)

Factors Affecting the Detection of Hexavalent Chromium in Cr-Contaminated Soil
por: Huang, Mingtao, et al.
Publicado: (2022)

Research on the performance of modified blue coke in adsorbing hexavalent chromium
por: Wang, Hua, et al.
Publicado: (2023)

Effect of hexavalent chromium on growth performance and metabolism in broiler chicken
por: Zhuo, Guorong, et al.
Publicado: (2023)

Efficient Biosorption of Hexavalent Chromium from Water with Human Hair
por: Prakash, Vivek, et al.
Publicado: (2022)

Solid-Phase Synthesis of Red Fluorescent Carbon Dots for the Dual-Mode Detection of Hexavalent Chromium and Cell Imaging
por: Hu, Jinshuang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j1bfdom4g5ug03i7qp714r7ai2