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Structural basis for the inhibition of Mycobacterium tuberculosis l,d-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains

Difficulty in the treatment of tuberculosis and growing drug resistance in Mycobacterium tuberculosis (Mtb) are a global health issue. Carbapenems inactivate l,d-transpeptidases; meropenem, when administered with clavulanate, showed in vivo activity against extensively drug-resistant Mtb strains. Ld...

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Detalles Bibliográficos
Autores principales:	Kim, Hyoun Sook, Kim, Jieun, Im, Ha Na, Yoon, Ji Young, An, Doo Ri, Yoon, Hye Jin, Kim, Jin Young, Min, Hye Kyeoung, Kim, Soon-Jong, Lee, Jae Young, Han, Byung Woo, Suh, Se Won
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2013
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605043/ https://www.ncbi.nlm.nih.gov/pubmed/23519417 http://dx.doi.org/10.1107/S0907444912048998

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