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Connecting the Kinetics and Energy Landscape of tRNA Translocation on the Ribosome
Functional rearrangements in biomolecular assemblies result from diffusion across an underlying energy landscape. While bulk kinetic measurements rely on discrete state-like approximations to the energy landscape, single-molecule methods can project the free energy onto specific coordinates. With me...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605090/ https://www.ncbi.nlm.nih.gov/pubmed/23555233 http://dx.doi.org/10.1371/journal.pcbi.1003003 |