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Under-Dominance Constrains the Evolution of Negative Autoregulation in Diploids

Regulatory networks have evolved to allow gene expression to rapidly track changes in the environment as well as to buffer perturbations and maintain cellular homeostasis in the absence of change. Theoretical work and empirical investigation in Escherichia coli have shown that negative autoregulatio...

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Detalles Bibliográficos
Autores principales: Stewart, Alexander J., Seymour, Robert M., Pomiankowski, Andrew, Reuter, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605092/
https://www.ncbi.nlm.nih.gov/pubmed/23555226
http://dx.doi.org/10.1371/journal.pcbi.1002992