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Under-Dominance Constrains the Evolution of Negative Autoregulation in Diploids
Regulatory networks have evolved to allow gene expression to rapidly track changes in the environment as well as to buffer perturbations and maintain cellular homeostasis in the absence of change. Theoretical work and empirical investigation in Escherichia coli have shown that negative autoregulatio...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605092/ https://www.ncbi.nlm.nih.gov/pubmed/23555226 http://dx.doi.org/10.1371/journal.pcbi.1002992 |