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Impact of type 2 diabetes on lower urinary tract symptoms in men: a cohort study

BACKGROUND: Studies of the impact of type 2 diabetes on the prevalence and incidence of lower urinary tract symptoms (LUTS) among men have provided divergent results. We sought to examine this issue using two large and diverse cohorts. METHODS: This study used questionnaire and clinical data from tw...

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Autores principales: Van Den Eeden, Stephen K, Ferrara, Assiamira, Shan, Jun, Jacobsen, Steven J, Quinn, Virginia P, Haque, Reina, Quesenberry, Charles P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605100/
https://www.ncbi.nlm.nih.gov/pubmed/23421436
http://dx.doi.org/10.1186/1471-2490-13-12
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author Van Den Eeden, Stephen K
Ferrara, Assiamira
Shan, Jun
Jacobsen, Steven J
Quinn, Virginia P
Haque, Reina
Quesenberry, Charles P
author_facet Van Den Eeden, Stephen K
Ferrara, Assiamira
Shan, Jun
Jacobsen, Steven J
Quinn, Virginia P
Haque, Reina
Quesenberry, Charles P
author_sort Van Den Eeden, Stephen K
collection PubMed
description BACKGROUND: Studies of the impact of type 2 diabetes on the prevalence and incidence of lower urinary tract symptoms (LUTS) among men have provided divergent results. We sought to examine this issue using two large and diverse cohorts. METHODS: This study used questionnaire and clinical data from two large multiethnic cohorts, the California Men’s Health Study (CMHS) and Research Program in Genes, Environment and Health (RPGEH). Diabetes characteristics data were derived from questionnaire and Diabetes Registry data. LUTS were measured using a standardized scale. Socioeconomic and comorbidity data were obtained by self-report. Multivariable logistic regression analysis was used to examine the association between baseline DM status and prevalence and incidence of LUTS, with adjustment for potential confounding variables. RESULTS: We found type 2 diabetes to be associated with prevalent LUTS (odds ratio (OR) = 1.32, 95% confidence interval (CI) 1.26, 1.38). The association was stronger among men with type 2 diabetes who were on active pharmaceutical treatment and had it for a longer duration. No association was observed between type 2 diabetes and new onset LUTS. CONCLUSIONS: Type 2 diabetes increases the risk of LUTS.
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spelling pubmed-36051002013-03-22 Impact of type 2 diabetes on lower urinary tract symptoms in men: a cohort study Van Den Eeden, Stephen K Ferrara, Assiamira Shan, Jun Jacobsen, Steven J Quinn, Virginia P Haque, Reina Quesenberry, Charles P BMC Urol Research Article BACKGROUND: Studies of the impact of type 2 diabetes on the prevalence and incidence of lower urinary tract symptoms (LUTS) among men have provided divergent results. We sought to examine this issue using two large and diverse cohorts. METHODS: This study used questionnaire and clinical data from two large multiethnic cohorts, the California Men’s Health Study (CMHS) and Research Program in Genes, Environment and Health (RPGEH). Diabetes characteristics data were derived from questionnaire and Diabetes Registry data. LUTS were measured using a standardized scale. Socioeconomic and comorbidity data were obtained by self-report. Multivariable logistic regression analysis was used to examine the association between baseline DM status and prevalence and incidence of LUTS, with adjustment for potential confounding variables. RESULTS: We found type 2 diabetes to be associated with prevalent LUTS (odds ratio (OR) = 1.32, 95% confidence interval (CI) 1.26, 1.38). The association was stronger among men with type 2 diabetes who were on active pharmaceutical treatment and had it for a longer duration. No association was observed between type 2 diabetes and new onset LUTS. CONCLUSIONS: Type 2 diabetes increases the risk of LUTS. BioMed Central 2013-02-20 /pmc/articles/PMC3605100/ /pubmed/23421436 http://dx.doi.org/10.1186/1471-2490-13-12 Text en Copyright ©2013 Van Den Eeden et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Van Den Eeden, Stephen K
Ferrara, Assiamira
Shan, Jun
Jacobsen, Steven J
Quinn, Virginia P
Haque, Reina
Quesenberry, Charles P
Impact of type 2 diabetes on lower urinary tract symptoms in men: a cohort study
title Impact of type 2 diabetes on lower urinary tract symptoms in men: a cohort study
title_full Impact of type 2 diabetes on lower urinary tract symptoms in men: a cohort study
title_fullStr Impact of type 2 diabetes on lower urinary tract symptoms in men: a cohort study
title_full_unstemmed Impact of type 2 diabetes on lower urinary tract symptoms in men: a cohort study
title_short Impact of type 2 diabetes on lower urinary tract symptoms in men: a cohort study
title_sort impact of type 2 diabetes on lower urinary tract symptoms in men: a cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605100/
https://www.ncbi.nlm.nih.gov/pubmed/23421436
http://dx.doi.org/10.1186/1471-2490-13-12
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