DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition

BACKGROUND: The prevention of persistent human immunodeficiency virus type 1 (HIV-1) infection requires the clarification of the mode of viral transduction into resting macrophages. Recently, DNA double-strand breaks (DSBs) were shown to enhance infection by D64A virus, which has a defective integra...

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Detalles Bibliográficos
Autores principales: Koyama, Takayoshi, Sun, Binlian, Tokunaga, Kenzo, Tatsumi, Masashi, Ishizaka, Yukihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605128/
https://www.ncbi.nlm.nih.gov/pubmed/23432899
http://dx.doi.org/10.1186/1742-4690-10-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605128/
https://www.ncbi.nlm.nih.gov/pubmed/23432899
http://dx.doi.org/10.1186/1742-4690-10-21

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