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DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition

BACKGROUND: The prevention of persistent human immunodeficiency virus type 1 (HIV-1) infection requires the clarification of the mode of viral transduction into resting macrophages. Recently, DNA double-strand breaks (DSBs) were shown to enhance infection by D64A virus, which has a defective integra...

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Detalles Bibliográficos
Autores principales:	Koyama, Takayoshi, Sun, Binlian, Tokunaga, Kenzo, Tatsumi, Masashi, Ishizaka, Yukihito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605128/ https://www.ncbi.nlm.nih.gov/pubmed/23432899 http://dx.doi.org/10.1186/1742-4690-10-21

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