Cargando…

Restriction of diverse retroviruses by SAMHD1

BACKGROUND: SAMHD1 is a triphosphohydrolase that restricts the replication of HIV-1 and SIV in myeloid cells. In macrophages and dendritic cells, SAMHD1 restricts virus replication by diminishing the deoxynucleotide triphosphate pool to a level below that which supports lentiviral reverse transcript...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gramberg, Thomas, Kahle, Tanja, Bloch, Nicolin, Wittmann, Sabine, Müllers, Erik, Daddacha, Waaqo, Hofmann, Henning, Kim, Baek, Lindemann, Dirk, Landau, Nathaniel R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605129/ https://www.ncbi.nlm.nih.gov/pubmed/23497255 http://dx.doi.org/10.1186/1742-4690-10-26

Ejemplares similares

SAMHD1 Restricts HIV-1 Replication and Regulates Interferon Production in Mouse Myeloid Cells
por: Zhang, Ruonan, et al.
Publicado: (2014)

TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infection of monocytes
por: Hofmann, Henning, et al.
Publicado: (2016)

The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation
por: Herrmann, Alexandra, et al.
Publicado: (2018)

Samhd1 knockout mice: modeling retrovirus restriction in vivo
por: Wu, Li
Publicado: (2013)

SAMHD1 specifically restricts retroviruses through its RNase activity
por: Choi, Jongsu, et al.
Publicado: (2015)

Viral Particle-Mediated SAMHD1 Depletion Sensitizes Refractory Glioblastoma to DNA-Damaging Therapeutics by Impairing Homologous Recombination
por: Daddacha, Waaqo, et al.
Publicado: (2022)

SAMHD1 … and Viral Ways around It
por: Deutschmann, Janina, et al.
Publicado: (2021)

Mouse SAMHD1 Has Antiretroviral Activity and Suppresses a Spontaneous Cell-Intrinsic Antiviral Response
por: Behrendt, Rayk, et al.
Publicado: (2013)

Phosphorylation of murine SAMHD1 regulates its antiretroviral activity
por: Wittmann, Sabine, et al.
Publicado: (2015)

Correction to: The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation
por: Herrmann, A., et al.
Publicado: (2018)

Spontaneous Type I IFN response in SAMHD1-deficient mice requires both, functional intracellular RNA and DNA sensing pathways
por: Behrendt, R, et al.
Publicado: (2015)

SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks
por: Kapoor-Vazirani, Priya, et al.
Publicado: (2022)

TRIM19/PML Restricts HIV Infection in a Cell Type-Dependent Manner
por: Kahle, Tanja, et al.
Publicado: (2015)

DNA damage induces a SAMHD1-mediated block to the infection of macrophages by HIV-1
por: Jáuregui, Paula, et al.
Publicado: (2018)

Restrictive influence of SAMHD1 on Hepatitis B Virus life cycle
por: Sommer, Andreas F. R., et al.
Publicado: (2016)

Functionality of Redox-Active Cysteines Is Required for Restriction of Retroviral Replication by SAMHD1
por: Wang, Zhonghua, et al.
Publicado: (2018)

Interplay of ancestral non-primate lentiviruses with the virus-restricting SAMHD1 proteins of their hosts
por: Mereby, Sarah A., et al.
Publicado: (2018)

Cellular and Biochemical Mechanisms of the Retroviral Restriction Factor SAMHD1
por: Wu, Li
Publicado: (2013)

Leishmania Induces Survival, Proliferation and Elevated Cellular dNTP Levels in Human Monocytes Promoting Acceleration of HIV Co-Infection
por: Mock, David J., et al.
Publicado: (2012)

Host SAMHD1 protein restricts endogenous reverse transcription of HIV-1 in nondividing macrophages
por: Mahboubi, Bijan, et al.
Publicado: (2018)

Retroviruses, retroelements and their restrictions
por: Koito, Atsushi, et al.
Publicado: (2013)

Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction, and cellular dNTP levels
por: Schüssler, Moritz, et al.
Publicado: (2023)

Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction and cellular dNTP levels
por: Schüssler, Moritz, et al.
Publicado: (2023)

Host Factor SAMHD1 Restricts DNA Viruses in Non-Dividing Myeloid Cells
por: Hollenbaugh, Joseph A., et al.
Publicado: (2013)

Equine lentivirus counteracts SAMHD1 restriction by Rev-mediated degradation of SAMHD1 via the BECN1-dependent lysosomal pathway
por: Ren, Huiling, et al.
Publicado: (2020)

SAMHD1 Functions and Human Diseases
por: Coggins, Si’Ana A., et al.
Publicado: (2020)

Substrates and Inhibitors of SAMHD1
por: Hollenbaugh, Joseph A., et al.
Publicado: (2017)

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac
por: Brandariz-Nuñez, Alberto, et al.
Publicado: (2012)

Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction
por: Arnold, Laurence H., et al.
Publicado: (2015)

SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells
por: Martinat, Charlotte, et al.
Publicado: (2021)

SAMHD1: a new insight into HIV-1 restriction in myeloid cells
por: St Gelais, Corine, et al.
Publicado: (2011)

A G1‐like state allows HIV‐1 to bypass SAMHD1 restriction in macrophages
por: Mlcochova, Petra, et al.
Publicado: (2017)

Mouse APOBEC3 Restriction of Retroviruses
por: Salas-Briceno, Karen, et al.
Publicado: (2020)

SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells
por: Descours, Benjamin, et al.
Publicado: (2012)

Interferon-inducible SAMHD1 restricts viral replication through downregulation of lipid synthesis
por: An, Ni, et al.
Publicado: (2022)

Attenuation of reverse transcriptase facilitates SAMHD1 restriction of HIV-1 in cycling cells
por: Tsai, Ming-Han C., et al.
Publicado: (2023)

Evolutionary Toggling of Vpx/Vpr Specificity Results in Divergent Recognition of the Restriction Factor SAMHD1
por: Fregoso, Oliver I., et al.
Publicado: (2013)

SAMHD1: a new contributor to HIV-1 restriction in resting CD4(+) T-cells
por: Wu, Li
Publicado: (2012)

PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation
por: Miyakawa, Kei, et al.
Publicado: (2019)

Cell-to-Cell Spreading of HIV-1 in Myeloid Target Cells Escapes SAMHD1 Restriction
por: Xie, Maorong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8nqqiggrgpojh35f5130lagpgk