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Enterovirus 71 Protease 2A(pro) Targets MAVS to Inhibit Anti-Viral Type I Interferon Responses
Enterovirus 71 (EV71) is the major causative pathogen of hand, foot, and mouth disease (HFMD). Its pathogenicity is not fully understood, but innate immune evasion is likely a key factor. Strategies to circumvent the initiation and effector phases of anti-viral innate immunity are well known; less w...
Autores principales: | Wang, Bei, Xi, Xueyan, Lei, Xiaobo, Zhang, Xiaoyan, Cui, Sheng, Wang, Jianwei, Jin, Qi, Zhao, Zhendong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605153/ https://www.ncbi.nlm.nih.gov/pubmed/23555247 http://dx.doi.org/10.1371/journal.ppat.1003231 |
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