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Genome-wide Determinants of Proviral Targeting, Clonal Abundance and Expression in Natural HTLV-1 Infection

The regulation of proviral latency is a central problem in retrovirology. We postulate that the genomic integration site of human T lymphotropic virus type 1 (HTLV-1) determines the pattern of expression of the provirus, which in turn determines the abundance and pathogenic potential of infected T c...

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Detalles Bibliográficos
Autores principales:	Melamed, Anat, Laydon, Daniel J., Gillet, Nicolas A., Tanaka, Yuetsu, Taylor, Graham P., Bangham, Charles R. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605240/ https://www.ncbi.nlm.nih.gov/pubmed/23555266 http://dx.doi.org/10.1371/journal.ppat.1003271

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