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Dendritic Cell-induced Activation of Latent HIV-1 Provirus in Actively Proliferating Primary T Lymphocytes
HIV-1 latency remains a formidable barrier towards virus eradication as therapeutic attempts to purge these reservoirs are so far unsuccessful. The pool of transcriptionally silent proviruses is established early in infection and persists for a lifetime, even when viral loads are suppressed below de...
Autores principales: | van der Sluis, Renée M., van Montfort, Thijs, Pollakis, Georgios, Sanders, Rogier W., Speijer, Dave, Berkhout, Ben, Jeeninga, Rienk E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605277/ https://www.ncbi.nlm.nih.gov/pubmed/23555263 http://dx.doi.org/10.1371/journal.ppat.1003259 |
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