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Structure of Human Cytomegalovirus UL141 Binding to TRAIL-R2 Reveals Novel, Non-canonical Death Receptor Interactions

The TRAIL (TNF-related apoptosis inducing ligand) death receptors (DRs) of the tumor necrosis factor receptor superfamily (TNFRSF) can promote apoptosis and regulate antiviral immunity by maintaining immune homeostasis during infection. In turn, human cytomegalovirus (HCMV) expresses immunomodulator...

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Detalles Bibliográficos
Autores principales:	Nemčovičová, Ivana, Benedict, Chris A., Zajonc, Dirk M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605307/ https://www.ncbi.nlm.nih.gov/pubmed/23555243 http://dx.doi.org/10.1371/journal.ppat.1003224

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