Recombinant salmonella-based 4-1BBL vaccine enhances T cell immunity and inhibits the development of colorectal cancer in rats: in vivo effects of vaccine containing 4-1BBL

BACKGROUND: Immunotherapy with vaccines is attractive for the treatment of cancer. This study is aimed at determining the effect of recombinant Salmonella (SL3261)-based 4-1BB ligand (4-1BBL) vaccine on the development of colorectal cancers and the potential immune mechanisms in rats. RESULTS: In co...

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Detalles Bibliográficos
Autores principales: Ye, Jianxin, Li, Ling, Zhang, Yuanting, Zhang, Xueguang, Ren, Daming, Chen, Weichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605352/
https://www.ncbi.nlm.nih.gov/pubmed/23413971
http://dx.doi.org/10.1186/1423-0127-20-8

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