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Antitumor effects of L-BLP25 Antigen-Specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model
BACKGROUND: L-BLP25 antigen-specific cancer immunotherapeutic agent is currently in phase III clinical trials for non-small cell lung cancer. Using a novel human MUC1 transgenic (hMUC1.Tg) lung cancer mouse model, we evaluated effects of L-BLP25 combined with low-dose cyclophosphamide (CPA) pretreat...
Autores principales: | Wurz, Gregory T, Gutierrez, Audrey M, Greenberg, Brittany E, Vang, Daniel P, Griffey, Stephen M, Kao, Chiao-Jung, Wolf, Michael, DeGregorio, Michael W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605365/ https://www.ncbi.nlm.nih.gov/pubmed/23496860 http://dx.doi.org/10.1186/1479-5876-11-64 |
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