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Post-traumatic vancomycin-resistant enterococcal endophthalmitis

The emergence of antibiotic-resistant organisms among severe ocular infections is of grave concern. We describe the first reported case of vancomycin-resistant enterococcal endophthalmitis following ocular trauma, uniquely caused by Enterococcus gallinarum. The organism demonstrated intrinsic resist...

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Detalles Bibliográficos
Autores principales: Hillier, Roxane J, Arjmand, Parnian, Rebick, Gabriel, Ostrowski, Mario, Muni, Rajeev H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605398/
https://www.ncbi.nlm.nih.gov/pubmed/23514354
http://dx.doi.org/10.1186/1869-5760-3-42
Descripción
Sumario:The emergence of antibiotic-resistant organisms among severe ocular infections is of grave concern. We describe the first reported case of vancomycin-resistant enterococcal endophthalmitis following ocular trauma, uniquely caused by Enterococcus gallinarum. The organism demonstrated intrinsic resistance to ceftazidime and vancomycin but responded favorably to a combination of intravitreal and intravenous ampicillin, plus intravitreal amikacin. When faced with a multidrug-resistant organism, the ophthalmologist must consider alternative antibiotic strategies.