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Bapineuzumab Alters Aβ Composition: Implications for the Amyloid Cascade Hypothesis and Anti-Amyloid Immunotherapy

The characteristic neuropathological changes associated with Alzheimer’s disease (AD) and other lines of evidence support the amyloid cascade hypothesis. Viewing amyloid deposits as the prime instigator of dementia has now led to clinical trials of multiple strategies to remove or prevent their form...

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Detalles Bibliográficos
Autores principales: Roher, Alex E., Cribbs, David H., Kim, Ronald C., Maarouf, Chera L., Whiteside, Charisse M., Kokjohn, Tyler A., Daugs, Ian D., Head, Elizabeth, Liebsack, Carolyn, Serrano, Geidy, Belden, Christine, Sabbagh, Marwan N., Beach, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605408/
https://www.ncbi.nlm.nih.gov/pubmed/23555764
http://dx.doi.org/10.1371/journal.pone.0059735