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Bapineuzumab Alters Aβ Composition: Implications for the Amyloid Cascade Hypothesis and Anti-Amyloid Immunotherapy
The characteristic neuropathological changes associated with Alzheimer’s disease (AD) and other lines of evidence support the amyloid cascade hypothesis. Viewing amyloid deposits as the prime instigator of dementia has now led to clinical trials of multiple strategies to remove or prevent their form...
Autores principales: | Roher, Alex E., Cribbs, David H., Kim, Ronald C., Maarouf, Chera L., Whiteside, Charisse M., Kokjohn, Tyler A., Daugs, Ian D., Head, Elizabeth, Liebsack, Carolyn, Serrano, Geidy, Belden, Christine, Sabbagh, Marwan N., Beach, Thomas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605408/ https://www.ncbi.nlm.nih.gov/pubmed/23555764 http://dx.doi.org/10.1371/journal.pone.0059735 |
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