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Hypersensitive Detection and Quantitation of BoNT/A by IgY Antibody against Substrate Linear-Peptide
Botulinum neurotoxin A (BoNT/A), the most acutely poisonous substance to humans known, cleave its SNAP-25 substrate with high specificity. Based on the endopeptidase activity, different methods have been developed to detect BoNT/A, but most lack ideal reproducibility or sensitivity, or suffer from l...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605418/ https://www.ncbi.nlm.nih.gov/pubmed/23555605 http://dx.doi.org/10.1371/journal.pone.0058908 |