Cargando…

Ability of Innate Defence Regulator Peptides IDR-1002, IDR-HH2 and IDR-1018 to Protect against Mycobacterium tuberculosis Infections in Animal Models

Tuberculosis is an ongoing threat to global health, especially with the emergence of multi drug-resistant (MDR) and extremely drug-resistant strains that are motivating the search for new treatment strategies. One potential strategy is immunotherapy using Innate Defence Regulator (IDR) peptides that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rivas-Santiago, Bruno, Castañeda-Delgado, Julio E., Rivas Santiago, Cesar E., Waldbrook, Matt, González-Curiel, Irma, León–Contreras, Juan C., Enciso-Moreno, Jose Antonio, del Villar, Victor, Mendez-Ramos, Jazmin, Hancock, Robert E. W., Hernandez-Pando, Rogelio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605426/ https://www.ncbi.nlm.nih.gov/pubmed/23555622 http://dx.doi.org/10.1371/journal.pone.0059119

Ejemplares similares

Synthetic Cationic Peptide IDR-1018 Modulates Human Macrophage Differentiation
por: Pena, Olga M., et al.
Publicado: (2013)

Impacts of PEGylation and Glycosylation on the Biological Properties of Host Defense Peptide IDR1018
por: Etayash, Hashem, et al.
Publicado: (2023)

Synthetic host defense peptide IDR-1002 reduces inflammation in Pseudomonas aeruginosa lung infection
por: Wuerth, Kelli C., et al.
Publicado: (2017)

IDR knowledge base for primary immunodeficiencies
por: Samarghitean, Crina, et al.
Publicado: (2007)

Modulation of the immune response by the host defense peptide IDR-1002 in chicken hepatic cell culture
por: Sebők, Csilla, et al.
Publicado: (2023)

IDR muon capture front end and variations
por: Neuffer, David, et al.
Publicado: (2012)

Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts
por: Turner-Brannen, Emily, et al.
Publicado: (2011)

IDR2D identifies reproducible genomic interactions
por: Krismer, Konstantin, et al.
Publicado: (2020)

Characterization of Host Responses during Pseudomonas aeruginosa Acute Infection in the Lungs and Blood and after Treatment with the Synthetic Immunomodulatory Peptide IDR-1002
por: Wuerth, Kelli, et al.
Publicado: (2018)

Liposome-Encapsulated Tobramycin and IDR-1018 Peptide Mediated Biofilm Disruption and Enhanced Antimicrobial Activity against Pseudomonas aeruginosa
por: Alzahrani, Nouf M., et al.
Publicado: (2022)

One Step Closer to the Understanding of the Relationship IDR-LCR-Structure
por: Gonçalves-Kulik, Mariane, et al.
Publicado: (2023)

The Cup Anemometer, a Fundamental Meteorological Instrument for the Wind Energy Industry. Research at the IDR/UPM Institute
por: Pindado, Santiago, et al.
Publicado: (2014)

Synthetic Cationic Peptide IDR-1002 and Human Cathelicidin LL37 Modulate the Cell Innate Response but Differentially Impact PRRSV Replication in vitro
por: Levast, Benoît, et al.
Publicado: (2019)

Generation of functional oligopeptides that promote osteogenesis based on unsupervised deep learning of protein IDRs
por: Cai, Mingxiang, et al.
Publicado: (2022)

Kbus/Idr, a mutant mouse strain with skeletal abnormalities and hypophosphatemia: Identification as an allele of 'Hyp'
por: Moriyama, Kenji, et al.
Publicado: (2011)

Tests sanguins de la tuberculose chez l’enfant, complémentaires de l’IDR
por: Retbi, Jean-Marc
Publicado: (2011)

Comparative Assessment of ADA, IDRS, and FINDRISC in Predicting Prediabetes and Diabetes Mellitus in South Indian Population
por: Doddamani, Parveen, et al.
Publicado: (2021)

IDR-induced CAR condensation improves the cytotoxicity of CAR-Ts against low-antigen cancers
por: Zhang, Xinyan, et al.
Publicado: (2023)

Data on evolution of intrinsically disordered regions of the human kinome and contribution of FAK1 IDRs to cytoskeletal remodeling
por: Kathiriya, Jaymin J., et al.
Publicado: (2016)

Arg/Lys-containing IDRs are cryptic binding domains for ATP and nucleic acids that interplay to modulate LLPS
por: Dang, Mei, et al.
Publicado: (2022)

LEF1 enhances β-catenin transactivation through IDR-dependent liquid–liquid phase separation
por: Zhao, Bing, et al.
Publicado: (2023)

The Combination of Synoeca-MP Antimicrobial Peptide with IDR-1018 Stimulates Proliferation, Migration, and the Expression of Pro-Regenerative Genes in Both Human Skin Cell Cultures and 3D Skin Equivalents
por: Alencar-Silva, Thuany, et al.
Publicado: (2023)

reactIDR: evaluation of the statistical reproducibility of high-throughput structural analyses towards a robust RNA structure prediction
por: Kawaguchi, Risa, et al.
Publicado: (2019)

Application of Indian Diabetic Risk Score (IDRS) and Community Based Assessment Checklist (CBAC) as Metabolic Syndrome prediction tools
por: Gupta, Manoj Kumar, et al.
Publicado: (2023)

Peptide IDR-1002 Inhibits NF-κB Nuclear Translocation by Inhibition of IκBα Degradation and Activates p38/ERK1/2–MSK1-Dependent CREB Phosphorylation in Macrophages Stimulated with Lipopolysaccharide
por: Huante-Mendoza, Alejandro, et al.
Publicado: (2016)

Relationship between low tube voltage (70 kV) and the iodine delivery rate (IDR) in CT angiography: An experimental in-vivo study
por: Lell, Michael M., et al.
Publicado: (2017)

Is anti‐viral defence the evolutionary origin of mRNA turnover? (Comment on DOI 10.1002/bies.201600100)
por: Rehwinkel, Jan
Publicado: (2016)

Innate Defense Regulator Peptide 1018 in Wound Healing and Wound Infection
por: Steinstraesser, Lars, et al.
Publicado: (2012)

Tuberculin skin test and interferon-gamma release assay values are associated with antimicrobial peptides expression in polymorphonuclear cells during latent tuberculous infection
por: Castañeda-Delgado, Julio E, et al.
Publicado: (2014)

Downregulation of sCD40 and sCTLA4 in Recovered COVID-19 Patients with Comorbidities
por: Méndez-Frausto, Gwendolyne, et al.
Publicado: (2022)

1,25-Dihydroxyvitamin D(3) Induces LL-37 and HBD-2 Production in Keratinocytes from Diabetic Foot Ulcers Promoting Wound Healing: An In Vitro Model
por: Gonzalez-Curiel, Irma, et al.
Publicado: (2014)

CpG 1018 Is an Effective Adjuvant for Influenza Nucleoprotein
por: Li, Yibo, et al.
Publicado: (2023)

Lipid Metabolism Alterations in a Rat Model of Chronic and Intergenerational Exposure to Arsenic
por: Rivas-Santiago, Cesar, et al.
Publicado: (2019)

Variability in the virulence of specific Mycobacterium tuberculosis clinical isolates alters the capacity of human dendritic cells to signal for T cells
por: Ramos-Martinez, Ana Gabriela, et al.
Publicado: (2019)

Peptide 1018 inhibits swarming and influences Anr-regulated gene expression downstream of the stringent stress response in Pseudomonas aeruginosa
por: Wilkinson, Lauren V., et al.
Publicado: (2021)

Structure and Biological Roles of Sinorhizobium fredii HH103 Exopolysaccharide
por: Rodríguez-Navarro, Dulce N., et al.
Publicado: (2014)

1018 Risk Factors for Surgical Site Infection Following Cardiovascular Surgery
por: Snyder, Graham, et al.
Publicado: (2014)

Prospects for B ®hh at LHCb
por: Rodrigues, E
Publicado: (2008)

The Recombinant Bacille Calmette–Guérin Vaccine VPM1002: Ready for Clinical Efficacy Testing
por: Nieuwenhuizen, Natalie E., et al.
Publicado: (2017)

Draft Genome Sequence of Pectobacterium wasabiae Strain CFIA1002
por: Yuan, Kat (Xiaoli), et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_40aaparhu7e45hioi8a3p145kh