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The aged niche disrupts muscle stem cell quiescence
The niche is a conserved regulator of stem cell quiescence and function. During aging, stem cell function declines. To what extent and by which means age-related changes within the niche contribute to this phenomenon are unknown. We demonstrate that the aged muscle stem cell niche, the muscle fiber,...
Autores principales: | Chakkalakal, Joe V., Jones, Kieran M., Basson, M. Albert, Brack, Andrew S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605795/ https://www.ncbi.nlm.nih.gov/pubmed/23023126 http://dx.doi.org/10.1038/nature11438 |
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