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Ubiquitin chain conformation regulates recognition and activity of interacting proteins

Mechanisms of protein recognition have been extensively studied for single-domain proteins(1), but are less well characterized for dynamic multi-domain systems. Ubiquitin (Ub) chains represent a biologically important multi-domain system that requires recognition by structurally diverse Ub-interacti...

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Detalles Bibliográficos
Autores principales: Ye, Yu, Blaser, Georg, Horrocks, Mathew H., Ruedas-Rama, Maria J., Ibrahim, Shehu, Zhukov, Alexander A., Orte, Angel, Klenerman, David, Jackson, Sophie E., Komander, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605796/
https://www.ncbi.nlm.nih.gov/pubmed/23201676
http://dx.doi.org/10.1038/nature11722