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Ubiquitin chain conformation regulates recognition and activity of interacting proteins
Mechanisms of protein recognition have been extensively studied for single-domain proteins(1), but are less well characterized for dynamic multi-domain systems. Ubiquitin (Ub) chains represent a biologically important multi-domain system that requires recognition by structurally diverse Ub-interacti...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605796/ https://www.ncbi.nlm.nih.gov/pubmed/23201676 http://dx.doi.org/10.1038/nature11722 |