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Targeted Ablation of miR-21 Decreases Murine Eosinophil Progenitor Cell Growth
MiR-21 is one of the most up-regulated miRNAs in multiple allergic diseases associated with eosinophilia and has been shown to positively correlate with eosinophil levels. Herein, we show that miR-21 is up-regulated during IL-5-driven eosinophil differentiation from progenitor cells in vitro. Target...
Autores principales: | Lu, Thomas X., Lim, Eun-Jin, Itskovich, Svetlana, Besse, John A., Plassard, Andrew J., Mingler, Melissa K., Rothenberg, Joelle A., Fulkerson, Patricia C., Aronow, Bruce J., Rothenberg, Marc E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606295/ https://www.ncbi.nlm.nih.gov/pubmed/23533623 http://dx.doi.org/10.1371/journal.pone.0059397 |
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