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Rgs13 Constrains Early B Cell Responses and Limits Germinal Center Sizes

Germinal centers (GCs) are microanatomic structures that develop in secondary lymphoid organs in response to antigenic stimulation. Within GCs B cells clonally expand and their immunoglobulin genes undergo class switch recombination and somatic hypermutation. Transcriptional profiling has identified...

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Detalles Bibliográficos
Autores principales: Hwang, Il-Young, Hwang, Kyung-Sun, Park, Chung, Harrison, Kathleen A., Kehrl, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606317/
https://www.ncbi.nlm.nih.gov/pubmed/23533672
http://dx.doi.org/10.1371/journal.pone.0060139