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Rgs13 Constrains Early B Cell Responses and Limits Germinal Center Sizes
Germinal centers (GCs) are microanatomic structures that develop in secondary lymphoid organs in response to antigenic stimulation. Within GCs B cells clonally expand and their immunoglobulin genes undergo class switch recombination and somatic hypermutation. Transcriptional profiling has identified...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606317/ https://www.ncbi.nlm.nih.gov/pubmed/23533672 http://dx.doi.org/10.1371/journal.pone.0060139 |