Cargando…
Rgs13 Constrains Early B Cell Responses and Limits Germinal Center Sizes
Germinal centers (GCs) are microanatomic structures that develop in secondary lymphoid organs in response to antigenic stimulation. Within GCs B cells clonally expand and their immunoglobulin genes undergo class switch recombination and somatic hypermutation. Transcriptional profiling has identified...
Autores principales: | Hwang, Il-Young, Hwang, Kyung-Sun, Park, Chung, Harrison, Kathleen A., Kehrl, John H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606317/ https://www.ncbi.nlm.nih.gov/pubmed/23533672 http://dx.doi.org/10.1371/journal.pone.0060139 |
Ejemplares similares
-
TLR4 signaling augments B lymphocyte migration and overcomes the restriction that limits access to germinal center dark zones
por: Hwang, Il-Young, et al.
Publicado: (2009) -
Variations in Gnai2 and Rgs1 Expression Affect Chemokine Receptor Signaling and the Organization of Secondary Lymphoid Organs
por: Hwang, II-Young, et al.
Publicado: (2010) -
Loss of Gα(i) proteins impairs thymocyte development, disrupts T-cell trafficking, and leads to an expanded population of splenic CD4(+)PD-1(+)CXCR5(+/−) T-cells
por: Hwang, Il-Young, et al.
Publicado: (2017) -
Normal Autophagic Activity in Macrophages from Mice Lacking Gα(i3), AGS3, or RGS19
por: Vural, Ali, et al.
Publicado: (2013) -
Gα(i) Signaling Promotes Marginal Zone B Cell Development by Enabling Transitional B Cell ADAM10 Expression
por: Hwang, Il-Young, et al.
Publicado: (2018)