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Redox-Sensitive Up-Regulation of eNOS by Purple Grape Juice in Endothelial Cells: Role of PI3-Kinase/Akt, p38 MAPK, JNK, FoxO1 and FoxO3a
The vascular protective effect of grape-derived polyphenols has been attributable, in part, to their direct action on blood vessels by stimulating the endothelial formation of nitric oxide (NO). The aim of the present study was to determine whether Concord grape juice (CGJ), which contains high leve...
Autores principales: | Alhosin, Mahmoud, Anselm, Eric, Rashid, Sherzad, Kim, Jong Hun, Frota Madeira, Socorro Vanesca, Bronner, Christian, Schini-Kerth, Valérie B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606366/ https://www.ncbi.nlm.nih.gov/pubmed/23533577 http://dx.doi.org/10.1371/journal.pone.0057883 |
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